Mary
12-18-2008, 07:34 AM
Ovarian, Breast And Lung Cancer Survival Linked To Two Proteins
18 Dec 2008
US scientists found that levels of two proteins called Dicer and Drosher that are involved in shutting down genes were linked to a woman's chances of surviving ovarian cancer and similar effects were also found in lung and breast cancer patients. Women with high levels of these proteins had a median survival of 11 years while women with low levels of both proteins only had a median survival rate of 2.7 years.
The study was the work of Dr Anil Sood, professor in the departments of Gynecologic Oncology and Cancer Biology at MD Anderson Cancer Center in Houston, Texas, and colleagues from other research centres in the US, and is published in the 18 December issue of the New England Journal of Medicine, NEJM.
Dicer and Drosher are important players in a process called RNA interference which shuts down genes inside cells. Sood and colleagues found that when this process stops, ovarian cancer patient outcomes are poor; they also found similar effects in lung and breast cancer patients. The study is thought to be the largest and most comprehensive example of the effect of RNA interference on cancer.
More on
http://www.medicalnewstoday.com/articles/133454.php
18 Dec 2008
US scientists found that levels of two proteins called Dicer and Drosher that are involved in shutting down genes were linked to a woman's chances of surviving ovarian cancer and similar effects were also found in lung and breast cancer patients. Women with high levels of these proteins had a median survival of 11 years while women with low levels of both proteins only had a median survival rate of 2.7 years.
The study was the work of Dr Anil Sood, professor in the departments of Gynecologic Oncology and Cancer Biology at MD Anderson Cancer Center in Houston, Texas, and colleagues from other research centres in the US, and is published in the 18 December issue of the New England Journal of Medicine, NEJM.
Dicer and Drosher are important players in a process called RNA interference which shuts down genes inside cells. Sood and colleagues found that when this process stops, ovarian cancer patient outcomes are poor; they also found similar effects in lung and breast cancer patients. The study is thought to be the largest and most comprehensive example of the effect of RNA interference on cancer.
More on
http://www.medicalnewstoday.com/articles/133454.php